Project assistant, 6 months, at The Department of Molecular Biology - Befattningen är under tillsättning eller redan tillsatt, och det är inte längre möjligt att lämna in en ansökan

The Department of Molecular Biology is looking for a project assistant for the project "Quantitative modelling of T-cells". The position is temporary for 6 months on full time with expected start 1 February 2020 or as agreed. Last day to apply is 13 December 2019.

Project description and work tasks

T-cells, an important part of the adaptive immune system, are involved in a large number of processes - from combating cancer, viruses, and parasites, to several pathogenic conditions such as asthma. As such they have been intensively studied. A challenge is now to connect all the studies into a single body of useful knowledge that can enable a holistic understanding of the T cells under various conditions.

In this project we are building an AI using advanced regression models. As input we are generating new high-throughput datasets under well-controlled in vitro conditions. This ranges from bulk RNA-seq and proteomics to several single-cell protocols.

This is a pilot study (6 months) with the aim of investigating the potential of the project to be appropriate for a grant application, PhD- or post-doc project.

The project assistant will under supervision of the groupleader:

• Analyze existing datasets to inform future planning of assays
• Implement several high-throughput wet lab protocols
• Test cell isolation methods and set up the cell culture
• Perform analysis of data for the integration into the computational model, with a focus on RNA-seq data.

The selected candidate will under supervision of the group leader implement several high-throughput wet lab protocols. Then using R and Python (along with suitable libraries), analyze existing and generated datasets, and document and present the findings.

For questions regarding the position contact Johan Henriksson, johan.henriksson@umu.se

Qualifications

You must hold a University degree equivalent to a European University Master degree in molecular biology, at the time of the recruitment (240 ECTS). You should have experience of programming (Python, R), especially RNA-seq analysis and network inference (e.g Cytoscape, clustering methods). You should be familiar with cell culture. Further you should know common protocols such as RNA/DNA extraction and cloning. You should have performed basic realtime microscopy and image analysis. You need to have a very good ability to communicate and write in English. You should be highly motivated and able to work productively in a team. Excellent communication skills for interacting effectively with senior colleagues and peers are required.

Application

You apply through our recruitment system 13 December 2019 at the latest. Your application must contain the following documents written in English or Swedish:

• A CV with information on education, a list of previous and current employments, and a list of publications.
• A cover letter describing your research experience and interests and motivation for applying for the position.
• Contact details of two to three references.

More about us

The Johan Henriksson lab is part of the Laboratory for Molecular Infection Medicine Sweden (MIMS) and the Umeå Centre for Microbial Research (UCMR), an interdisciplinary research center devoted to top quality research and novel applications in the field of microbiology. You can find more information about us at www.henlab.org; www.ucmr.umu.se, and www.umu.se/en/department-of-molecular-biology.