Umeå University, Medicinska fakulteten

Umeå University is one of Sweden’s largest higher education institutions with over 37,000 students and about 4,700 employees. The University offers a diversity of high-quality education and world-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything is close. Our cohesive campuses make it easy to meet, work together and exchange knowledge, which promotes a dynamic and open culture.

The ongoing societal transformation and large green investments in northern Sweden create enormous opportunities and complex challenges. For Umeå University, conducting research about – and in the middle of – a society in transition is key. We also take pride in delivering education to enable regions to expand quickly and sustainably. In fact, the future is made here.

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The Faculty of Medicine, which consists of 13 departments, is responsible for biomedical research and courses in the field of nursing and health care and has an extensive research and graduate education in more than 80 subjects.

Description of the PhD-project:

 Understanding the process of skill acquisition is a long-standing topic in neuroscience. During learning, the brain initially tries out numerous candidate circuits until the best candidate circuit is selected for further local fine-tuning. During the first phase, this process is hypothesized to be associated with growth of brain structure, which partially retracts after the best circuit for the job has been selected. This PhD project aims at applying advanced imaging techniques during skill acquisition to monitor skill-related brain structure changes in different model systems to establish a mechanistic understanding of the dynamics of brain plasticity. Special focus is given to the magnetic resonance imaging (MRI) techniques voxel-based morphometry (VBM) and diffusion tensor imaging (DTI) in order to monitor and quantify in vivo processes during learning. Furthermore, histology and whole-mount brain immunohistochemistry will be used as an ex vivo method to correlate MRI-based findings.

Qualifications:

Applicants must:

1) hold a University degree of at least 240 ECTS or equivalent or

2) have 120 Swedish (old) credits (Swe. poäng; corresponding to 180 ECTS credits) of higher education studies in the same fields or equivalent taken before July 1, 2007.

Other merits:

In addition, the applicant should, through university studies or other equivalent education, have gained basic theoretical knowledge in biomedicine and have outstanding experience in laboratory work and method development. Applicants with practical experience of research with animal models and tissue handling are prioritized and those with experience working with MRI is considered an additional significant strength and will be prioritized. Experience with immunohistochemistry and other biochemical methods of analysis are also considered strengths. The applicant must be able to work both independently and as part of a team, and high focus will be given to the candidate’s potential collaborative skills.

Specific admission requirements:

In order to be admitted to postgraduate studies, it is required that the applicant has:

  • necessary knowledge from university higher education or corresponding education and/or special professional experience that is assessed in relation to the research area.
  • necessary English language skills, both in writing and in speaking. Evaluation of these skills is made by having the intended PhD student present his/her research plan in English for the Department’s designated postgraduate education group.

Further information: Dr. Daniel Marcellino, daniel.marcellino@umu.se

Start date: As soon as possible, or upon agreement.

 Other information: https://www.umu.se/en/research/doctoral-studies/

Type of employment Temporary position
Contract type Full time
First day of employment As soon as possible, or upon agreement
Salary Monthly salary
Number of positions 1
Full-time equivalent 100%
City Umeå
County Västerbottens län
Country Sweden
Reference number AN 2.2.1-339-19
Contact
  • Forskarassistent Daniel Marcellino, epost: daniel.marcellino@umu.se
Union representative
  • SACO, 090-786 53 65
  • SEKO, 090-786 52 96
  • ST, 090-786 54 31
Published 27.Feb.2019
Last application date 22.Mar.2019 11:59 PM CET

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