Postdoctor, 2 years, DNA interstrand crosslink repair in humans

The Department of Molecular Biology seeks a postdoctoral researcher who will study DNA interstrand crosslink repair in humans. The employment is full-time for two years in the first instance, starting as soon as possible upon agreement.

Project description and work tasks 

The focus of the research is to understand the molecular mechanisms of DNA interstrand crosslink repair and the Fanconi Anemia DNA repair pathway, which plays a key role in genome stability in humans. The postdoctor will study our recent findings, using biochemistry, live-cell imaging, CRISPR/Cas9-mediated genome engineering and cryo-EM.

See our lab page for more details www.umu.se/en/research/groups/martin-cohn/.

You will have access to outstanding research facilities and networking opportunities offered in Umeå.

Qualifications

To be appointed under the postdoctoral agreement, the postdoctoral fellow is required to have completed a doctoral degree, or a foreign degree deemed equivalent to a doctoral degree, in a relevant subject. This qualification requirements must be fulfilled no later than at the time of the appointment decision.

To be appointed under the postdoctoral agreement, priority should be given to candidates who completed their doctoral degree, according to what is tipulated in the paragraph above, no later than three years prior. If there are special reasons, candidates who completed their doctoral degree prior to that may also be eligible. Special reasons include absence due to illness, parental leave, appointments of trust in trade union organisations, military service, or similar circumstances, as well as clinical practice or other forms of appointment/assignment relevant to the subject area. Postdoctoral fellows who are to teach or supervise must have taken relevant courses in teaching and learning in higher education.

Additional requirements are:

• Previous experience in expression and purification of recombinant proteins.
• Experience in genetic engineering of human cell lines.
• A proven research record in biochemical and cell biological research.
• Previous experience of contributing to publications.
• Be highly motivated with good communication skills and have the ability to work as part of a team.

Application

A full application should include: 

• Cover letter in which you describe your interest in the post and how you believe your research experience would contribute to our research. 
• Curriculum vitae (CV) with publication list.
• Copy of doctoral degree certificate or documentation that clarifies when the degree of doctor is expected to be obtained.
• Copies of available diplomas, showing completed courses and grades.
• Contact information to two persons willing to act as references.

References will be requested in connection with potential interview. 

The application must be written in English (preferably) or Swedish. The application is made through our electronic recruitment system. Last day to apply is 13 December 2024. 

Further details can be provided by Martin Cohn (martin.cohn@umu.se).

More information

Umeå is located next to the polar circle with the nature just around the corner and is a city with an international, welcoming, open attitude and a high quality of life, which makes this a great place to live and work. The university and the Department of Molecular Biology has a long-standing tradition of big discoveries and is the birthplace of the CRISPR/Cas9 discovery leading to the Nobel Prize. At the Department of Molecular Biology, we aim to understand complex biological problems such as cancer, infection, immunology, physiology and behaviour. We offer a stimulating, internationally diverse and highly collaborative work environment and competitive salary. You will also find yourself as part of the strongest research environment in Sweden, equipped with cutting-edge research facilities. The surrounding research teams include members from across the world and English is the natural used language at the Department