Doctoral student (PhD-position) in medical sciences, surgery - ,
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Umeå University, Faculty of Medicine
Umeå University is one of Sweden’s largest higher education institutions with over 37,000 students and about 4,700 employees. The University offers a diversity of high-quality education and world-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything is close. Our cohesive campuses make it easy to meet, work together and exchange knowledge, which promotes a dynamic and open culture.
The ongoing societal transformation and large green investments in northern Sweden create enormous opportunities and complex challenges. For Umeå University, conducting research about – and in the middle of – a society in transition is key. We also take pride in delivering education to enable regions to expand quickly and sustainably. In fact, the future is made here.
Are you interested in learning more? Read about Umeå university as a workplace
The Faculty of Medicine, which consists of 12 departments, is responsible for biomedical research and courses in the field of nursing and health care and has an extensive research and graduate education in more than 80 subjects.
At the Department of Surgical and Perioperative Science, we have internationally recognized research environments. Within the discipline of surgery, we have a strong tradition of translational research and we run our own research laboratory within the Translational Research Centre. Read more about the department and our subjects at the Department of Surgical and Perioperative Sciences website (umu.se).
We are now looking for a doctoral student in surgery for a laboratory research project. The employment period is four years and is full-time, starting on 28 August 2023 or by agreement.
Those admitted to doctoral studies are included in the faculty-wide doctoral programme at the Faculty of Medicine. The programme comprises 25 credits and is offered in two study rates: 25 credits over 8 semesters (4 years in total) and over 12 semesters (6 years in total), with programme start every autumn and spring semester. More information about the programme can be found on the faculty's website for doctoral studies. (Doctoral Studies at the Faculty of Medicine – Handbook (umu.se)).
Project description and tasks
Our group studies evolutionary conserved signalling networks that can act as cancer drivers and aim to find tractable pharmacological targets and novel lead molecules within that niche. We focus on tumours harbouring activating mutations in the MAPK/ERK signalling pathway. To this end we have developed a powerful in vivo screening platform using the small nematode Caenorhabditis elegans. This allows us to screen for novel tumour suppressing drugs and genes. Positive findings will be genetically characterized in C. elegans and validated functionally in human cancer models. Novel drug candidates will be further developed in collaboration with CBCS in Umeå. The project is supervised by associate professor Oskar Hemmingsson and senior science engineer Ola Billing. Read more about the project here: https://www.umu.se/en/research/projects/cancer-research-oskar-hemmingsson/
The position aims for a PhD degree. The accepted student commits to her/his research education, which includes project lab work, mandatory courses, journal clubs, seminar series, etc.
Admission requirements
To be admitted to a doctoral programme, the applicant must have basic eligibility, specific eligibility and be assessed as having the ability required to complete the programme.
Basic eligibility
General entry requirements for doctoral studies are met by those who have completed a degree at advanced level, fulfilled course requirements of at least 240 higher education credits (credits), of which at least 60 credits are at advanced level, or who have acquired essentially equivalent knowledge in some other way in Sweden or abroad. (HF 7 kap 39§).
Specialised expertise
To be admitted to a doctoral programme, the applicant must have the necessary knowledge from higher education or equivalent education and/or professional experience that is assessed in relation to the doctoral programme area, as well as the necessary language skills in English. Both written and oral skills are required. Assessment of these skills is carried out by a prospective doctoral student presenting their research plan in English to an assessment group appointed by the head of department.
Additional qualifications
The successful applicant is required to have a solid lab experience and a basic education within medicine, biomedicine, molecular biology, or similar. Experience in C. elegans or other model organisms would be an advantage. Experience in genetics and pharmacology as well as experience with 2D and 3D cell culturing will be appreciated. Personal suitability, interpersonal skills, and excellent written and oral English communication skills will be required.
Application
The application shall contain:
- A personal letter explaining why you are applying and why you are suitable for the doctoral programme.
- Curriculum vitae. (CV)
- Certified copies of diplomas, degrees, and certificates.
- Copies of the thesis and any publications.
- Contact details of at least two reference persons.
The application must be written in Swedish or English. Applications must be submitted via our e-recruitment system Varbi and be received no later than 28 August 2023.
| Type of employment | Temporary position |
|---|---|
| Contract type | Full time |
| Salary | Monthly salary |
| Number of positions | 1 |
| Full-time equivalent | 100% |
| City | Umeå |
| County | Västerbottens län |
| Country | Sweden |
| Reference number | AN 2.2.1-1116-23 |
| Contact |
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| Union representative |
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| Published | 12.Jun.2023 |
| Last application date | 28.Aug.2023 11:59 PM CEST |