Senior research engineer to the Department of Molecular Biology - Befattningen är under tillsättning eller redan tillsatt, och det är inte längre möjligt att lämna in en ansökan
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Umeå University, Faculty of Medicine
Umeå University is one of Sweden’s largest higher education institutions with over 37,000 students and about 4,700 employees. The University offers a diversity of high-quality education and world-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything is close. Our cohesive campuses make it easy to meet, work together and exchange knowledge, which promotes a dynamic and open culture.
The ongoing societal transformation and large green investments in northern Sweden create enormous opportunities and complex challenges. For Umeå University, conducting research about – and in the middle of – a society in transition is key. We also take pride in delivering education to enable regions to expand quickly and sustainably. In fact, the future is made here.
Are you interested in learning more? Read about Umeå university as a workplace
The Faculty of Medicine, which consists of 13 departments, is responsible for biomedical research and courses in the field of nursing and health care and has an extensive research and graduate education in more than 80 subjects.
The Department of Molecular Biology is looking for a senior research engineer for a full-time position until further notice, probationary period may be applied. Access according to agreement.
Description of work tasks
The goal of the project is to study the role of RNA modifications in breast cancer metastasis under the supervision of Associate Professor Francesca Aguilo. RNA modifications can respond rapidly to a variety of stimuli, particularly stress, without the need for activation of new time-consuming transcriptional programs. During tumorigenesis, proliferating cancer cells encounter various cellular stresses, and the adaptation to such stresses is an important driver of cancer cell survival. The applicant will combine genetic, biochemical, biological and genome-wide approaches to decipher how altered patterns of RNA modifications contribute to metastatic breast cancer. 2D and 3D cell culture models, patient samples, as well as mouse orthotopic transplantation will be used to study the central RNA-based regulatory circuitry in breast tumorigenesis.
Qualifications
Candidates must hold a University degree equivalent to a European University PhD degree in Molecular biology (or equivalent fields) at the time of the recruitment. In addition, the applicant should have gained experience in RNA modifications, including genome-wide technologies to profile N6-methyladenosine. Basic theoretical knowledge in RNA modifications and epigenetics, and have good experience of laboratory work, method development, and different biochemical methods of analysis are also required. Practical experience of cell culture with breast cancer models is a merit. The ideal candidate should be able to pursue challenging tasks, solve problems and achieve objectives, and do so in intense collaboration and communication with other researchers.
Candidates must be fluent in spoken and written English and highly motivated.
Application
You apply through our recruitment system at the latest 25 May 2023. Your application must contain the following documents written in English (preferably) or Swedish:
- A CV with information on education, a list of previous and current employments, and a list of publications.
- A cover letter describing your research experience and interests and motivation for applying for the position.
- Copy of doctoral degree
- Contact details of two to three references.
More about us
For further information contact Francesca Aguilo (francesca.aguilo@umu.se). For more information about the Department of Molecular Biology, please visit our website http://www.umu.se/molbiol.
We are looking forward to receive your application!
| Type of employment | Permanent position |
|---|---|
| Contract type | Full time |
| First day of employment | By agreement |
| Salary | Monthly salary |
| Number of positions | 1 |
| Full-time equivalent | 100% |
| City | Umeå |
| County | Västerbottens län |
| Country | Sweden |
| Reference number | AN 2.2.1-845-23 |
| Contact |
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| Union representative |
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| Published | 04.May.2023 |
| Last application date | 25.May.2023 11:59 PM CEST |