Postdoctoral position in experimental oncology - ,
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Umeå University, Department of Radiation Sciences
Umeå University is one of Sweden’s largest higher education institutions with over 37,000 students and about 4,700 employees. The University offers a diversity of high-quality education and world-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything is close. Our cohesive campuses make it easy to meet, work together and exchange knowledge, which promotes a dynamic and open culture.
The ongoing societal transformation and large green investments in northern Sweden create enormous opportunities and complex challenges. For Umeå University, conducting research about – and in the middle of – a society in transition is key. We also take pride in delivering education to enable regions to expand quickly and sustainably. In fact, the future is made here.
Are you interested in learning more? Read about Umeå university as a workplace
The Department of Radiation Sciences is, in terms of research, a dynamic and internationally successful environment in diagnostic radiology, oncology, cognitive neuroscience, radiation physics and bio-medical engineering. The department belongs to the Faculty of Medicine at Umeå University.
This appointment is a part of a strategic initiative from the Faculty of Medicine and aims to stimulate innovative and interdisciplinary research. The appointment is a full-time, fixed-term position for two years. The project aim is to evaluate a novel approach for cancer therapeutics that enables the patient’s own immune system to fight off the cancer. Application deadline 11 March 2022.
Description of the project
The applicant will work within a translational immune oncology project for therapeutic and prophylactic vaccination against cancer by using an RNA-based delivery system. The hypothesis is that cancer-specific immunity can be induced by utilization of novel neoantigens enriched on extrachromosomal DNA molecules. The successful candidate will work on identification of cancer specific neoantigens and the construction of personalized RNA vaccines. A number of animal models will be used to verify immunogenicity and protective potential of candidate vaccines, either as monotherapies or in combination with checkpoint inhibitors.
Work responsibilities
The postdoctoral researcher will be working both with planning and evaluation of experimental research work in collaboration with other researches linked to the project. The research assignments include identification of relevant neoantigens from sequencing data to the formulation of a personalized vaccine and treatment. This includes running DNA/RNA sequencing experiments, bioinformatic processing of data, and construction of a personalized RNA vaccines. The applicant will also conduct animal experiments to test the efficacy of the RNA cancer vaccines.
Eligibility
A person who has been awarded a doctorate or a foreign qualification deemed to be the equivalent of a doctorate in biomedicine, immunology, molecular biology or related discipline is eligible for appointment as postdoctoral researcher. This eligibility requirement must be met no later than the time at which the appointment decision is made.
We are looking for candidates with experience in next-generation sequencing, both in setting up sequencing experiments and downstream data analyses. General knowledge in molecular biology techniques are required and a strong background in immunology is considered as beneficial. It is important that you re able to work in a team as well as independently. Good oral and written communication skills in English are required.
Additional useful qualifications
Since appointment as a postdoctoral researcher is a career-development position for junior researchers, we are primarily interested in applicants who completed their doctoral degree no more than three years before the application deadline. If there are special reasons, an applicant who has completed their degree earlier than that may be considered. Special reasons include absence due to illness, parental leave, clinical practice, appointments of trust for a trade union organisation or other similar circumstances, and for relevant duties/assignments within the subject area.
More information about the position
The appointment is a full-time, fixed-term position for two years in accordance with the terms of contract for fixed-term employment as a postdoctoral researcher from 1 February 2022.
More information about the group's research can be found on our website https://www.umu.se/en/research/groups/nilsson-group/
Application
The application must include:
- A brief description of your research interests and a statement describing why you are interested in the position.
- CV
- List of publications
- Degree certificate from doctoral studies and other relevant degrees
- Contact details of two reference persons
The application must be written in Swedish or English. The application must be made via our e-recruitment system Varbi and must be received latest 11 March 2022.
Other information
For additional information about the position, please contact Jonas Nilsson, jonas.a.nilsson@umu.se
More about us
For more information about the Department of Radiation Sciences, please visit our website
https://www.umu.se/en/department-of-radiation-sciences/
We look forward to receiving your application.
| Type of employment | Temporary position |
|---|---|
| Employment expires | 2024-12-31 |
| Contract type | Full time |
| Salary | Månadslön |
| Number of positions | 1 |
| Full-time equivalent | 100% |
| City | Umeå |
| County | Västerbottens län |
| Country | Sweden |
| Reference number | AN 2.2.1-142-22 |
| Contact |
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| Union representative |
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| Published | 01.Feb.2022 |
| Last application date | 11.Mar.2022 11:59 PM CET |