Senior research engineer position in GPCR mediated oxygen sensation - Befattningen är under tillsättning eller redan tillsatt, och det är inte längre möjligt att lämna in en ansökan
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Umeå University, Medicinska fakulteten
Umeå University is one of Sweden’s largest higher education institutions with over 37,000 students and about 4,700 employees. The University offers a diversity of high-quality education and world-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything is close. Our cohesive campuses make it easy to meet, work together and exchange knowledge, which promotes a dynamic and open culture.
The ongoing societal transformation and large green investments in northern Sweden create enormous opportunities and complex challenges. For Umeå University, conducting research about – and in the middle of – a society in transition is key. We also take pride in delivering education to enable regions to expand quickly and sustainably. In fact, the future is made here.
Are you interested in learning more? Read about Umeå university as a workplace
The Faculty of Medicine, which consists of 13 departments, is responsible for biomedical research and courses in the field of nursing and health care and has an extensive research and graduate education in more than 80 subjects.
Applications are invited for a senior research engineer position in the laboratory of Dr. Changchun Chen at Umeå University, Sweden, working on oxygen sensation in the nematode C. elegans. The lab is affiliated to Wallenberg Center for Molecular Medicine (WCMM) and located in Umeå Center for Molecular Medicine (UCMM). The position is of two-year-full-time employment. This position will be available from January 2022.
Project description
The project aims at delineating how GPCR signaling modulates O2 sensation in the nematode C. elegans. C. elegans provides unique advantages to investigate the molecular mechanisms of acute O2 responses. It is amenable for large-scale forward genetic screens allowing functionally relevant molecules to be identified without prior knowledge. C. elegans genome encodes over 1000 GPCRs, which makes it challenging to link GPCRs to a given cellular process. This project involves a large-scale genetic screen and extensive calcium imaging analysis to thoroughly dissect the molecular and neural circuit bases of GPCR mediated O2 responses in C. elegans.
Qualifications
The candidate shall have a PhD in a relevant subject (biology, genetics or biochemistry. The candidate shall be able to work independently within a highly interactive group. The ideal candidate shall have demonstrated good knowledge in genetics, cell biology, biochemistry or relevant areas. Previous experience in high-throughput genetic screen, microinjection, CRISPR genome editing and calcium imaging analysis in C. elegans is essential.
Please submit your application in English, combined in one pdf file:
1. A cover letter including your past achievements and research interests
2. A curriculum vitae including publication list and the contact information of two references
Terms
Fulltime, limited to two years employment.
For more information, please contact Changchun Chen (changchun.chen@umu.se) and visit our webpage at (https://www.umu.se/en/research/groups/changchun-chen/).
| Type of employment | Temporary position |
|---|---|
| Contract type | Full time |
| First day of employment | enligt överenskommelse |
| Salary | Månadslön |
| Number of positions | 1 |
| Full-time equivalent | 100% |
| City | Umeå |
| County | Västerbottens län |
| Country | Sweden |
| Reference number | AN 2.2.1-1786-21 |
| Contact |
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| Union representative |
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| Published | 29.Nov.2021 |
| Last application date | 20.Dec.2021 11:59 PM CET |