Senior Research Assistant for studies on viral replication compartments - Befattningen är under tillsättning eller redan tillsatt, och det är inte längre möjligt att lämna in en ansökan
This advert is not available!
Umeå University, Medicinska fakulteten
Umeå University is one of Sweden’s largest higher education institutions with over 37,000 students and about 4,700 employees. The University offers a diversity of high-quality education and world-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything is close. Our cohesive campuses make it easy to meet, work together and exchange knowledge, which promotes a dynamic and open culture.
The ongoing societal transformation and large green investments in northern Sweden create enormous opportunities and complex challenges. For Umeå University, conducting research about – and in the middle of – a society in transition is key. We also take pride in delivering education to enable regions to expand quickly and sustainably. In fact, the future is made here.
Are you interested in learning more? Read about Umeå university as a workplace
The Faculty of Medicine, which consists of 13 departments, is responsible for biomedical research and courses in the field of nursing and health care and has an extensive research and graduate education in more than 80 subjects.
The department of Integrative Medical Biology announces a full time position as Senior Research Assistant in Dr. Richard Lundmark’s group.
Project description:
The successful applicant will participate within a research project headlined
"Mechanisms of viral factory generation". Following uptake into host cells, flaviviruses reprograms the cell into becoming a factory for the production of new viruses. The viral proteins induce the generation of cavities in cellular organelles, so called replication compartments, which protect the replicated RNA from detection and degradation by the cellular response system. Today, very little is known about the mechanisms that lead replication vesicle formation. We take a novel approach using the tick-borne encephalitis virus (TBEV) model system to characterize the mechanisms for how viral proteins remodel cellular membranes into replication vesicles.
The work includes design, cloning, and development of stable cell lines, protein purification, APEX-based screening and identification of interacting proteins using mass spectrometry, siRNA-based knock down, analysis of cell lines using fluorescent microscopy and electron microscopy.
Qualifications:
Eligible to apply are individuals with a PhD in a relevant area or equivalent scientific skills.
We are looking for enthusiastic candidates with experience from infectious studies and a biochemical and cell biological background. Prior experience of biochemistry, cell biology and imaging in active research lab will be an added advantage as well as experience of viral research. The successful candidate is expected to design and execute his or her project independently, but also work in close collaboration with the other members of the team.
Application should include:
1. A brief cover letter (about one page) that describes the applicants research experience, research interests, and suitability for the project.
2. Curriculum vitae including information about academic degrees (with verifications), technical expertise, employments, list of publications, and names and contact information for two references.
For more information, contact Assistant Professor Richard Lundmark, Department of Integrative Medical Biology, Umeå University, e-mail: richard.lundmark@umu.se
The position is for 18 months. Start date: October 1st, 2019 at the earliest, or upon agreement.
We look forward to receiving your application!
| Type of employment | Temporary position |
|---|---|
| Contract type | Full time |
| First day of employment | 2019-10-01, or upon agreement |
| Salary | Monthly salary |
| Number of positions | 1 |
| Full-time equivalent | 100% |
| City | Umeå |
| County | Västerbottens län |
| Country | Sweden |
| Reference number | AN 2.2.1-1196-19 |
| Contact |
|
| Union representative |
|
| Published | 15.Aug.2019 |
| Last application date | 09.Sep.2019 11:59 PM CEST |