PhD position in Molecular Biology - Befattningen är under tillsättning eller redan tillsatt, och det är inte längre möjligt att lämna in en ansökan
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Umeå University, Medicinska fakulteten
Umeå University is one of Sweden’s largest higher education institutions with over 37,000 students and about 4,700 employees. The University offers a diversity of high-quality education and world-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything is close. Our cohesive campuses make it easy to meet, work together and exchange knowledge, which promotes a dynamic and open culture.
The ongoing societal transformation and large green investments in northern Sweden create enormous opportunities and complex challenges. For Umeå University, conducting research about – and in the middle of – a society in transition is key. We also take pride in delivering education to enable regions to expand quickly and sustainably. In fact, the future is made here.
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The Faculty of Medicine, which consists of 13 departments, is responsible for biomedical research and courses in the field of nursing and health care and has an extensive research and graduate education in more than 80 subjects.
PhD position in Molecular Biology
We are looking for a PhD student in Medical Science with an orientation towards Molecular Biology and a special interest in infection and cancer. The position at the Department of Molecular Biology at Umeå University is temporary for four years to start 1 March or as agreed. Last day to apply is January 28th 2019.
PhD Project
This PhD project aims to investigate the role of membrane vesicle (MV)-associated bacterial protein toxins in epigenetic modulation of cell signaling and in carcinogenesis.
MVs are constantly discharged from bacteria during growth. We earlier demonstrated that MVs can play a role of physiological relevance in toxin release from bacteria and demonstrated that MVs released from bacteria are effective long distance vehicles of multifunctional cargos, from bacterial DNA and RNA to proteins including several toxins and immune modulators. Recently, our laboratory demonstrated a potential modulatory effect of bacterial MVs on tumor cell epigenetic regulation.
The PhD project aims to expand our knowledge of how MV-associated bacterial factors can modulate epigenetics and host cell signaling and to gain a better understanding of MV's beneficial contributions to potential protection against the appearance of cancer and the potential of MVs as new tools for nano-particle-based targeted cancer therapy.
Eligibility
To be admitted for studies at third-cycle level the applicant is required to have completed a second-cycle level degree, or completed course requirements of at least 240 ECTS credits, of which at least 60 ECTS credits are at second-cycle level, or have an equivalent education from abroad or equivalent qualifications. Required is a minimum of 30 credits in chemistry, including at least 7.5 credits biochemistry; 45 credits in biology or molecular biology with at least 7.5 credits in genetics and 22,5 credits in microbiology, physiology and cell-and molecular biology. Additionally, at least 45 credits from second cycle studies in cell- and molecular biology including an independent work of at least 15 credits is required.
Qualifications
You should be highly motivated and able to work productively in a team as well as independently. Excellent communication skills for interacting effectively with senior colleagues and peers are required.
The successful candidate has experience from work with pathogenic bacteria and both theoretical and experimental experience from analyses of epigenetic modulation of cancer cell signaling. You need to be fluent in spoken and written English, which will be evaluated by the postgraduate studies board of the department.
Basis of assessment
- Knowledge and skills relevant to doctoral studies within the research area
- The ability to formulate and solve scientific questions.
- Skills in written and oral communication in English.
- Other experience relevant to doctoral studies, such as professional experience.
Good collaborative skills, drive and independent work ability are considered as positive merits.
A selection will be made among qualified applicants on the basis of their qualifications and their ability to benefit from studies at the doctoral level. After the selection of the suitable candidate, the process for the admission to doctoral studies will commence. An admission decision will not be taken by the faculty’s director of studies until an individual study plan has been approved by the departmental admission board.
How to apply
You apply through our recruitment system. Your application must contain the following documents written in English or Swedish:
- A CV with information on education, a list of previous and current employments, and a list of publications.
- Copies of relevant degrees
- A cover letter describing research experience and interests, motivation for applying for the position
- Contact details of one to three references.
Union information is available from SACO, +46-(0)90-786 53 65, SEKO, +46-(0)90-786 52 96 and ST, +46-(0)90-786 54 31.
For questions regarding the position contact Professor Sun Nyunt Wai, e-mail: sun.nyunt.wai@umu.se
More about us
You can find more information about us at:
| Type of employment | Temporary position |
|---|---|
| Contract type | Full time |
| First day of employment | 2019-03-01 or as agreed |
| Salary | monthly salary |
| Number of positions | 1 |
| Full-time equivalent | 100% |
| City | Umeå |
| County | Västerbottens län |
| Country | Sweden |
| Reference number | AN 2.2.1-59-19 |
| Contact |
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| Union representative |
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| Published | 14.Jan.2019 |
| Last application date | 28.Jan.2019 11:59 PM CET |