Umeå universitet, Teknisk-naturvetenskaplig fakultet

Umeå University is one of Sweden’s largest higher education institutions with over 37,000 students and about 4,700 employees. The University offers a diversity of high-quality education and world-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything is close. Our cohesive campuses make it easy to meet, work together and exchange knowledge, which promotes a dynamic and open culture.

The ongoing societal transformation and large green investments in northern Sweden create enormous opportunities and complex challenges. For Umeå University, conducting research about – and in the middle of – a society in transition is key. We also take pride in delivering education to enable regions to expand quickly and sustainably. In fact, the future is made here.

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The Department of Chemistry is seeking a senior research engineer for a project on autophagy mechanisms. The employment is full-time and limited to 2018-12-31. Last day to apply is July 4, 2018.

Project description
One of the main interests of the group is a system that has been evaluated at the molecular and cellular level with a range of chemical, molecular and cell biological techniques concerns mechanism of autophagy. Autophagy is an evolutionarily conserved self-eating process mainly to eliminate or recycle dysfunctional cellular organelles or unused proteins. Autophagy plays an important role in physiology including development and ageing and has been associated with diverse human diseases, including cancer, neurodegeneration, cardiac hypertrophy, and pathogen infection. Autophagy modulation is implicated in the treatment of diseases such as neurodegeneration and cancer. Despite extensive work, the models of autophagosome formation and autophagy regulation are not yet well established. Our laboratory has elucidated fundamental mechanisms underlying autophagosome formation and new mechanisms of autophagy regulation. We will combine cell biological, biochemical, and novel chemical and chemo-optogenetic approaches to understand the mechanism of autophagic membrane morphogenesis.

Working tasks
The senior research engineer will work on, but not limited to:

  • design and conduct experiments in cell biological research on autophagy
  • process and analyse results and data
  • communicate results with the supervisor and other group members
  • elucidate the mechanisms of autophagosome formation using cell biological and biochemical methods
  • supervise students
  • write research papers

Competence requirements
The required qualification is a doctoral degree in cell biology or equivalent. The successful candidate should have more than 3 years of research experience at postdoctoral level in cell biology or related field. Documented experiences in autophagy research and cell biological techniques (stable cell lines, western blotting, siRNA, CRISPR-Cas and/or cell imaging) are strong merits. The candidate is expected to work independently but also in close collaboration with other members of the team, independence and good ability to collaborate is therefore a requirement. Good command of written and spoken English is also a requirement.

Application
The application shall be done via our e-recruitment system and be submitted July 4, 2018 at the latest. A complete application should include;

  • A cover letter including qualifications and motivation for applying (max 2 pages),
  • CV including list of publications,
  • Copies of degree certificates including doctoral degree,
  • Names and contact details of at least two reference persons.

The employment is full-time and limited to December 31, 2018. Starting date according to agreement.

For further information, please contact Professor Yaowen Wu, yaowen.wu@umu.se

About us
The Department of Chemistry is the largest department within the Faculty of Science and Technology with approximately 200 employees out of which 40 are doctoral students, and a strong and expanding research. Three major research areas, Biological Chemistry, Environmental and Biogeochemistry and Technical Chemistry collect the department's research and education in chemistry. We are also a strong partner in the KBC, Chemical-Biological Centre. For more information see www.chemistry.umu.se/eng

Type of employment Special fixed-term employment
Employment expires 2018-12-31
Contract type Full time
First day of employment According to agreement
Salary Monthly salary
Number of positions 1
Full-time equivalent 100%
City Umeå
County Västerbottens län
Country Sweden
Reference number AN 2.2.1-1158-18
Union representative
  • SACO, 090-786 53 65
  • SEKO, 090-786 52 96
  • ST, 090-786 54 31
Published 13.Jun.2018
Last application date 04.Jul.2018 11:59 PM CEST

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