Umeå University, Medicinska fakulteten

Umeå University is one of Sweden’s largest higher education institutions with over 37,000 students and about 4,700 employees. The University offers a diversity of high-quality education and world-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything is close. Our cohesive campuses make it easy to meet, work together and exchange knowledge, which promotes a dynamic and open culture.

The ongoing societal transformation and large green investments in northern Sweden create enormous opportunities and complex challenges. For Umeå University, conducting research about – and in the middle of – a society in transition is key. We also take pride in delivering education to enable regions to expand quickly and sustainably. In fact, the future is made here.

Are you interested in learning more? Read about Umeå university as a workplace

The Faculty of Medicine, which consists of 13 departments, is responsible for biomedical research and courses in the field of nursing and health care and has an extensive research and graduate education in more than 80 subjects.

The Department of Medical Biochemistry and Biophysics invites applicants for a 2-year postdoctoral position in Biochemistry. The employment is full-time and covers two years.

Project Description
Our research group studies the structural and molecular mechanisms of the transcriptional co-activator Mediator in yeast and plant cells. The overall goal of our work is to gain an increased understanding of how transcriptional regulation in response to different types of stress is controlled through the Mediator complex in yeast, S.cerevisiae. The project will involve molecular biology and biochemical techniques such as cloning, expression and purification of proteins, analysis of how Mediator binds to chromatin in a global perspective, how this binding change in response to stress and identification of other proteins and protein complexes that interact Mediator with in chromatin. The specific objective of the project is to clarify how Mediator influences the chromatic structure and gene expression globally in response to stress.

Qualifications
A doctoral degree in biochemistry or molecular biology is required. The applicant should have practical experience in protein purification and different types of global methods for studying gene expression and interaction of proteins with chromatin, such as RNAseq and ChIP-seq. A documented experience from working with S.cerevisiae as model system is a requirement. Previous experience from working with transcription regulation and transcription factors is highly credible. The applicant must master English both verbally and in writing.

Application
The application must consist of the following documents written in English or Swedish:

  1. A short personal letter with justification for the application.
  2. Curriculum vitae
  3. Strengthened copies of diplomas and grades.
  4. Contact information for at least two reference persons.

Documents sent electronically must be in Word or PDF format.

The application must be made via our e-recruitment system and be received by 2018-05-18. Date of access as agreed.

Further information is provided by Prof. Stefan Björklund, +46 70 2162890, stefan.bjorklund@umu.se

Type of employment Temporary position
Contract type Full time
Number of positions 1
Full-time equivalent 100%
City Umeå
County Västerbottens län
Country Sweden
Reference number AN 2.2.1-636-18
Contact
  • Stefan Björklund, stefan.bjorklund@umu.se
Union representative
  • SACO, 090-786 53 65
  • SEKO, 090-786 52 96
  • ST, 090-786 54 31
Published 13.Apr.2018
Last application date 18.May.2018 11:59 PM CEST

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