Postdoctoral position in pancreatic cancer research - Befattningen är under tillsättning eller redan tillsatt, och det är inte längre möjligt att lämna in en ansökan

We are currently looking for a postdoc in pancreatic cancer research for a period of two years starting in Spring 2024 or as agreed.

Description of the project and work responsibilities

Pancreatic cancer has a very high mortality rate and currently no effective treatment options are available. A unique feature of the disease is the pronounced fibrotic stroma that surrounds tumour cells. This tumour stroma consists of an extracellular matrix (ECM), fibroblasts, which together provide the cancer cells with important signals that regulate tumour growth. This makes the stroma an interesting target from a treatment perspective, but the lack of knowledge in the complexity of the stroma has hampered the development of drugs targeting stromal interactions.

In this project the impact of fibroblasts on the development of pancreatic cancer will be studied in detail. The pathophysiological role of fibroblasts in disease progression will be studied in animal models, human tissues, and organoid based co-culture systems. Potential drugs affecting the function of the fibroblasts will then be developed and tested. The overall aim is to identify and explore critical interactions between pancreatic cancer cells and fibroblasts, and to develop new therapeutic strategies that target the disease by selectively blocking or stimulating these interactions.

Eligibility

A person who has been awarded a doctorate or a foreign qualification deemed to be the equivalent of a doctorate in biomedicine or biochemistry is eligible for appointment as postdoctoral researcher. This eligibility requirement must be met no later than the time at which the appointment decision is made.

We are looking for a highly talented and motivated candidate with a record of productive research, and the ability to work independently as well as part of a team. Excellent verbal and written English communication skills are required.

Additional useful qualifications

Since appointment as a postdoctoral researcher is a career-development position for junior researchers, we are primarily interested in applicants who completed their doctoral degree no more than three years before the application deadline. If there are special reasons, an applicant who has completed their degree earlier than that may be considered. Special reasons include absence due to illness, parental leave, clinical practice, appointments of trust for a trade union organisation or other similar circumstances, and for relevant duties/assignments within the subject area.

Previous research experience in the field of the drug development and drug optimisation and cell-based and animal-based model systems are also of great merit. A strong background in molecular biology, biochemistry, and tumour biology is highly desirable.

More information about the position

The appointment is a full-time, fixed-term position for three years in accordance with the terms of contract for fixed-term employment as a postdoctoral researcher from 1 February 2022.

Application

The application must include:

• A brief description of your research interests and a statement describing why you are interested in the position.
• CV
• List of publications
• Degree certificate from doctoral studies and other relevant degrees
• Contact details of two reference persons

The application must be written in Swedish or English. The application must be made via our e-recruitment system Varbi and must be received latest 10 April 2024.

We look forward to receiving your application.